GuideGLP-1 Hub
GLP-1 Medications and Your Gallbladder: What to Watch For
A large review linked GLP-1 medications to a small increase in gallbladder problems. Here is what that means and which signs to know.
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News, research and clear explainers on GLP-1 medications.
GuideGLP-1 Hub
Vision Changes and GLP-1 Medications: Keeping It in Proportion
European regulators call NAION, a rare optic nerve problem, a very rare side effect of semaglutide medicines. Here is what that means and what to watch for.
GuideGLP-1 Hub
GLP-1 Medications and Your Liver
A 2025 trial tested a once-weekly GLP-1 medication in adults with fatty liver disease and scarring. Here is what it found, and the habits your liver likes.
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GLP-1 Medications and Knee Osteoarthritis Pain
A 2024 trial of people with obesity and knee osteoarthritis found bigger improvements in pain and function with semaglutide than with placebo. Here is what it showed, and what it does not tell us yet.
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GLP-1 Medications and Alzheimer’s Disease
Two large trials tested oral semaglutide in early Alzheimer’s disease. Here is what they found and what it means for you.
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GLP-1 Medications and Mood: Where Regulators Stand
After reports of suicidal thoughts, regulators reviewed GLP-1 medications. Here is where the European and U.S. reviews landed and what to do if your mood changes.
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GLP-1 Medications and Surgery: Why the Stomach Matters
GLP-1 medications slow how fast the stomach empties, which is why anesthesia teams plan around them. Here is how the guidance has changed and what to tell your care team.
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GLP-1 Medications for Teenagers
Obesity often begins in childhood. Here is what the main trial of a GLP-1 medication in adolescents measured, what happened afterward and what it cannot yet answer.
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Semaglutide and Alcohol Cravings: An Early Look at a Surprising Link
Some people on GLP-1 medications say they drink less. A small early trial looked at whether that is real, and what it can and cannot tell us.
GuideGLP-1 Hub
GLP-1 Medications and Kidney Health
A large trial in people with type 2 diabetes and kidney disease found a 24 percent lower risk of serious kidney and heart events with a once-weekly GLP-1 medication. Who was studied and what it means.